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Background: There is increasing evidence that AD progression differs by sex. Methods: This pilot study included 36 CU subjects age Using a voxel-wise analysis, we determined the sex differences in the association maps between CSF biomarkers and atrophy rates. We found a greater impact of the rest of CSF biomarkers in areas of the Papez circuit in women versus men. Men showed greater involvement in lateral parietal and paracentral areas. Discussion: suggest an early differential progression of brain atrophy between sexes.

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RSS Link Copy. Full text links Cite Display options Display options. Abstract Background: There is increasing evidence that AD progression differs by sex. Similar articles Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets. Falcon C, et al. Neuroimage Clin. Tarawneh R, et al. JAMA Neurol. Sutphen CL, et al.

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The association between biomarkers in cerebrospinal fluid and structural changes in the brain in patients with Alzheimer's disease. Li X, et al. J Intern Med. Epub Dec PMID: The application of cerebrospinal fluid biomarkers in early diagnosis of Alzheimer disease. Blennow K, Zetterberg H. Blennow K, et al. Med Clin North Am. Epub Feb 1. PMID: Review.

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See all similar articles. Jin Z, et al. Front Neurosci. Publication types Research Support, Non-U. Gov't Actions. MeSH terms Aged Actions. Atrophy Actions. Female Actions. Humans Actions. Male Actions. Middle Aged Actions. Pilot Projects Actions.

Sex Characteristics Actions. Substances Amyloid beta-Peptides Actions. Biomarkers Actions. Peptide Fragments Actions. Full text links [x] IOS Press. Copy Download.

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